Report DVT of Bilateral lower limbs till IVC in Thrombophilia Posted February 15, 2009 I too have a high cholesterol level. My level has been up to 12.9. I also have a pretty low Protein S level. I have previously posted a suggested area for further investigation about any possible link. I am not a Doctor, but (and it could be coincidence) people confirmed in my family who have PSD also have elevated (high) cholesterol. I am not saying there is a link, but until the question is asked there is no way of knowing. I would be interested in responses.